Contact us...
info@caleva.co.uk
Telephone:
44 1258 471122

 

To go directly to information about specific products click the link below:-

 

Formulation development

Mixer Torque Rheometer

Caleva Mini-kit

 

Extruders

Mini screw extruder

Extruder 20

Extruder 35

Extruder 40

Extruder 100

Custom built extruders

 

Spheronizers

Multi bowl laboratory spheronizer
Spheronizer 120

Spheronizer 380

Spheronizer 500

Spheronizer 700

Spheronizer 700 Twin

Continuous production

 

Tablet and spheroid coating

For more information please contact our partner in your country directly.

 

For technical advice or to discuss your needs without any obligation you can contact us directly by email on info@caleva.co.uk or by fax on #44 1258 47 11 33 or by phone on #44 1258 47 11 22.

 

Why not take advantage of our 40 yeas of experience with Extrusion  and Spheronization.

 

We will design and build production equipment around your specific requirements.

 

 

 

 


If you are in South Korea and want to find out more about the Caleva Mini Kit please contact our partner;
Dongwuk. C&I Co.

 
The Caleva Mini-kit for Pharmaceutical Formulation Development of Spheroids

Does your laboratory have a need to extrude and spheronize small quantities of material for research & development or quality control?

Do you have to do trials with less than 100g of dry powder?

Would you like to do the entire trial run from powder to spheroids in less than an hour?


Caleva Process Solutions is well known for its development of small scale equipment to monitor and develop formulations and manufacturing processes.

The “Caleva Mini Kit” is a set of three components designed to work together.

The Mini-kit is made up of:-

 

1.        The Mixer Torque Rheometer (MTR-3) for giving a quantified measurement describing properties of the powder to binder ratio in the formulation.

2.        The Caleva R&D Screw extruder will allow the extrusion of a few grams of material.

3.        A Caleva Multi Bowl Spheronizer system capable of working with quantities of a few grams of extruded product.

 

This system will  facilitate product development, with scale up potential, with very small samples of material (as little as 80g).


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The Mixer Torque Rheometer – 3 (MTR-2)

 

A well established formulation research and quality control tool in its own right that is easy to operate and rapid to produce results with the Caleva Mini-kit.  It is possible easily and quickly to establish the correct binder ratio and the optimum mix-time for any specific product combination. Materials can be checked in less than half an hour. If you want to know more then contact Caleva at info@caleva.co.uk.

 

 

The Caleva Mixer Torque Rheometer-3

 

 

The bench top stand alone Mini Screw Extruder

 

 

The Caleva Multi Bowl Spheronizer system with a 120 mm bowl attached



The Mini Screw Extruder

The mini-screw extruder was designed to be part of the caleva mini kitand to work together with the Mixer Torque Rheometer and the Micro Spheronizer.  We had several requests to supply the small extruder as a stand alone item to facilitate research and development with extrudates and spheroids on very small quantities of material.

 

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The Multi Bowl Spheronizer system with the 120 mm bowl

Four different diameter spheronizer bowls used on the same base Work with a wide range of batch sizes with a single apparatus.
Work with small samples when product is scarce or costly. Work with larger samples when larger samples can be tested or when trial quantities are required.

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Key points

A set of equipment designed to work together on the laboratory bench top.

The MTR facilitates the rapid determination of the optimum ratio of powder to liquid binder with about 20 gram of powder.

The Mini Screw Extruder allows the extrusion of quantities as small as 5-10g of wet mass.

The MBS with a 120 bowl and inserts as little as 1 gram of sample material.

Efficient operation when time and materials are scarce.


If you have at least 80g of powder to test and the “Caleva Mini Kit” within one hour you can:-

 

·    know the correct binder ratio needed for the formulation,

·    know the correct mixing time and,

·    have 40g of optimum quality spheroids produced.

  

Using the Caleva mini-kit for formulation development a small sample of optimum spheroids can quickly be made for additional testing and continued product development.

 

If you are looking for lab equipment for use in formulation development then ask us for more information about the Caleva Mini-kit at info@caleva.co.uk

 
Caleva Process Solutions Ltd.
Telephone: + 44 1258 47 11 22 / Fax: + 44 1258 47 11 33 / Email: info@caleva.co.uk
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