From powder to wet mass. · Do you need to determine the optimum liquid/binder concentration and the optimum mixing time (optimization of formulation parameters)? · Do you want the ability to use the results obtained as part of a scale up strategy? · Do you need to evaluate materials to determine formulation choices? The Mixer Torque Rheometer-2 can be used as a key tool in these investigations. With the MTR-2 you can:- · Quickly, consistently and reproducibly determine the optimum binder mix. · Study the effect of mixing kinetics on your formulation. · Study the effect of multiple binder additions for formulation development and screening. · Structure and determine your scale up strategy mixing parameters · Study mixing kinetics using variable mix times. Back to top... |
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From wet mass to coated spheroids With the extruder head attachment on the Mixer Torque Rheometer it is possible to make small quantities of extrudate (as little as 5g) that can be spheronized (pelletized) without wastage and by use of a minimum amount of material. With the Microspheronizer you can produce as little as 5g of spheroids, evaluate the spheronization characteristics of various formulations and establish parameters for a structured scale up. With the Fluid-bed Mini Coater Drier you can optimize film coating materials, reproducibly coat a few grams of spheroids and produce small samples of spheroids for pre-clinical trials Back to top...
From wet mass to coated tablets. The Mixer Torque Rheometer-2 will allow the optimum selection of materials, the optimization of binder content, the reproducible production of small quantities of granules and the planning of scale up procedures. The Fluid-bed Tablet Mini Coater Drier will allow (with a minimum of material – as little as a single tablet) the evaluation of suitability of tablet coating materials, the optimization of the film coating material using a very small number of tablets and the coating of exactly the required number of tablets without wasting material. |
